Fitted values of the L parameter for mutants with low- or medium-level constitutive activity
Mutant | ZM241385 | DPCPX | MRS1706 |
|---|---|---|---|
| F84L | 0.11 ± 0.02 | 0.12 ± 0.02 | 0.14 ± 0.02 |
| F84S | 0.22 ± 0.03 | 0.16 ± 0.02 | 0.22 ± 0.02 |
| F84L/S95G | 0.22 ± 0.02 | 0.17 ± 0.02 | 0.20 ± 0.02 |
| T42A | 0.20 ± 0.02 | 0.16 ± 0.02 | 0.18 ± 0.02 |
| T42A/V54A | 1.38 ± 0.10 | 1.6 ± 0.10 | 1.38 ± 0.08 |
| N36S/T42A | 1.49 ± 0.10 | 1.47 ± 0.10 | 1.52 ± 0.08 |
| N36S/T42A/T66A | 1.9 ± 0.17 | 1.69 ± 0.10 | 1.90 ± 0.11 |