TABLE 4

List of mutation sites found in cDNA of albumin genes from six strains of rats. Sequence results are compared with reference sequence (NM134326)


Mutation

Amino Acid Change

CD

Lewis

EHBR

SD

Brown Norway

Wistar
A114→G (Silent) WT WT WT G/G WT WT
T345→C (Silent) WT WT WT C/C C/C C/C
A736→C (Silent) WT WT WT C/C C/C C/C
G784→C Val238→Leu WT WT WT C/C C/C C/C
T786→C WT WT WT C/C C/C C/C
A846→G (Silent) WT WT WT G/G G/G G/G
C950→T Thr293→Ile WT WT WT T/T T/T T/T
C1236→A (Silent) WT WT A/A WT WT WT
C1257→T (Silent) WT WT WT T/T WT T/T
G1291→A Val407→Ile WTA WT A/A A/A A/A A/A
T1513→C
(Silent)
C/C
C/C
C/C
C/C
C/C
C/C
  • WT, wild type, where the nucleic acids correspond to those of the reference sequence.

    a A/G for one of four rats.