%0 Journal Article %A Bradford N. Craver %A Anne Cameron %A Walter Barrett %T SOME PHARMACOLOGICAL PROPERTIES OF A SERIES OF ACETAMIDINES AND PROPIONAMIDINES %D 1950 %J Journal of Pharmacology and Experimental Therapeutics %P 353-361 %V 99 %N 3 %X 1. The general pharmacological properties of a series of acetamidines and propionamidines have been presented. 2. A small minority of the amidines exhibited marked anticholinergic and somewhat less marked antihistaminic activity. The presumed structural requisites to those actions have been discussed. 3. A minority of the amidines comprised a second group that exhibited marked positive inotropic and chronotropic effects upon the perfused heart and the heartlung preparation. The presumed structural requisites to that action have been discussed in detail. %U https://jpet.aspetjournals.org/content/jpet/99/3/353.full.pdf