PT - JOURNAL ARTICLE AU - E. W. Maynert AU - H. B. Van Dyke TI - THE ABSENCE OF LOCALIZATION OF BARBITAL IN DIVISIONS OF THE CENTRAL NERVOUS SYSTEM DP - 1950 Feb 01 TA - Journal of Pharmacology and Experimental Therapeutics PG - 184--187 VI - 98 IP - 2 4099 - http://jpet.aspetjournals.org/content/98/2/184.short 4100 - http://jpet.aspetjournals.org/content/98/2/184.full SO - J Pharmacol Exp Ther1950 Feb 01; 98 AB - The view that barbital is excreted only as unchanged drug was confirmed by the use of barbital labeled with N15. The concentration of the isotopic barbital was determined in various parts of the brain of four dogs after doses ranging from 25 to 250 mgm. per kgm. No localization in a particular division of the central nervous system such as the diencephalon was present.