RT Journal Article SR Electronic T1 LIVER CELL ALTERATION AND DDT STORAGE IN THE FAT OF THE RAT INDUCED BY DIETARY LEVELS OF 1 TO 50 P. P. M. DDT JF Journal of Pharmacology and Experimental Therapeutics JO J Pharmacol Exp Ther FD American Society for Pharmacology and Experimental Therapeutics SP 268 OP 273 VO 98 IS 3 A1 EDWIN P. LAUG A1 ARTHUR A. NELSON A1 O. GARTH FITZHUGH A1 FRIEDA M. KUNZE YR 1950 UL http://jpet.aspetjournals.org/content/98/3/268.abstract AB 1. Accumulation of DIT in the fat occurs at every level of intake, down to and including 1 p. p. m. Greater storage is favored in the female. 2. With time there is a progressive rise in storage, reaching a maximum at 19 to 23 weeks. 3. The age of the animal does not appear to affect the rate at which DDT is stored in the fat. 4. From 50 to 75 per cent of the DDT stored in fat still remains one month after a DDT-free diet; 25 per cent remains after three months. 5. Hepatie cell alterations occur from diets containing as little as 5 p.p.m. of DDT. 1950 by The American Society for Pharmacology and Experimental Therapeutics