TY - JOUR T1 - THE ABSORPTION, DISTRIBUTION AND EXCRETION OF d,l METHADONE JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 222 LP - 228 VL - 97 IS - 2 AU - E. LEONG WAY AU - CHEN-YÜ SUNG AU - WILLIAM P. McKELWAY Y1 - 1949/10/01 UR - http://jpet.aspetjournals.org/content/97/2/222.abstract N2 - 1. A method for determining d,l methadone in biologic samples is described. 2. d,l Methadone is well absorbed when given orally. 3. The compound concentrates mainly in the liver, kidney, lungs and spleen. Low levels are found in blood, heart and muscle. 4. Only a very small fraction of d,l methadone appears in the feces and urine unchanged. ER -