RT Journal Article
SR Electronic
T1 THE GANGLIONIC BLOCKING ACTION OF "DIBUTOLINE"
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 38
OP 41
VO 96
IS 1
A1 Carl C. Gruhzit
A1 Gordon K. Moe
YR 1949
UL http://jpet.aspetjournals.org/content/96/1/38.abstract
AB Dibutoline, in addition to its atropine-like action, produces effects comparable with those of tetraethylammonium: (1) fall of heart rate and blood pressure with increased femoral blood flow; (2) abolition of the pressor response to carotid occlusion; (3) suppression of the pressor actions of nicotine and acetylcholine; (4) potentiation of the pressor effects of epinephrine. These actions were shown to be due to blockade of ganglionic transmission.