@article {Lands1, author = {A. M. Lands and Estelle Ananenko and Gwendolyn Jones and James O. Hoppe and T. J. Becker}, title = {THE ANTISPASMODIC ACTION OF BASIC NITRILES}, volume = {96}, number = {1}, pages = {1--10}, year = {1949}, publisher = {American Society for Pharmacology and Experimental Therapeutics}, abstract = {1. The methiodide salts of various diphenylaminoalkanenitriles have significant anticholinergic activity. 2. The nitrite group appears to be important for this anticholinergic action. 3. The most active quaternary salts in this group of compounds are effective antispasmodics when administered parenterally, sublingually or orally. 4. Acute intravenous toxicity of these quaternary salts in albino mice is relatively high; by contrast oral toxicity of two of these is low.}, issn = {0022-3565}, URL = {https://jpet.aspetjournals.org/content/96/1/1.2}, eprint = {https://jpet.aspetjournals.org/content/96/1/1.2.full.pdf}, journal = {Journal of Pharmacology and Experimental Therapeutics} }