TY - JOUR T1 - CENTRAL IMPAIRMENT OF SYMPATHETIC REFLEXES BY 8-AMINOQUINOLINES JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 407 LP - 414 VL - 95 IS - 3 AU - GORDON K. MOE AU - BRAULIO PERALTA AU - MAURICE H. SEEVERS Y1 - 1949/03/01 UR - http://jpet.aspetjournals.org/content/95/3/407.abstract N2 - 1. Pamaquine, pentaquine, and isopentaquine chronically administered to dogs produce impairment of sympathetic cardiovascular reflexes, but not of parasympathetic or respiratory reflexes. 2. Pentaquine and isopentaquine, but probably not pamaquine, cause similar effects in the monkey. 3. The impairment of reflexes is believed to be due to destruction of medullary cell-groups. 1949 by The American Society for Pharmacology and Experimental Therapeutics ER -