PT  - JOURNAL ARTICLE
AU  - ALBERT WOLLENBERGER
AU  - OTTO KRAYER
TI  - EXPERIMENTAL HEART FAILURE CAUSED BY CENTRAL NERVOUS SYSTEM DEPRESSANTS AND LOCAL ANESTHETICS
DP  - 1948 Dec 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 439--443
VI  - 94
IP  - 4
4099  - http://jpet.aspetjournals.org/content/94/4/439.short
4100  - http://jpet.aspetjournals.org/content/94/4/439.full
SO  - J Pharmacol Exp Ther1948 Dec 01; 94
AB  - Heart failure was produced in the heart-lung preparation of the dog by the administration of the following compounds: the central nervous system depressants, pentobarbital, chlorobutanol, paraldehyde, propazone, diphenylhydantoin, and trimethadione; and the local anesthetics, cocaine, procaine, and tetracaine. A comparison has been made of the intensity of the negative inotropic cardiac action of these compounds, and other phases of their toxic action on the heart have been described. 1948 by The American Society for Pharmacology and Experimental Therapeutics