PT - JOURNAL ARTICLE AU - William P. Anslow, Jr. AU - David A. Karnofsky AU - B. Val Jager AU - Homer W. Smith TI - THE INTRAVENOUS, SUBCUTANEOUS AND CUTANEOUS TOXICITY OF <em>bis</em>(β-CHLOROETHYL) SULFIDE (MUSTARD GAS) AND OF VARIOUS DERIVATIVES DP - 1948 May 01 TA - Journal of Pharmacology and Experimental Therapeutics PG - 1--9 VI - 93 IP - 1 4099 - http://jpet.aspetjournals.org/content/93/1/1.short 4100 - http://jpet.aspetjournals.org/content/93/1/1.full SO - J Pharmacol Exp Ther1948 May 01; 93 AB - The parenteral toxicity of bis(β-chloroethyl) sulfide (mustard gas) and certain mustard derivatives has been studied in various species. Most derivatives of mustard are relatively non-toxic. Those which are toxic are shown to act in a different manner from mustard. These data support the hypothesis that mustard acts either per se or in the form of its first aqueous reaction product, β-chloro-ethyl-ethylene sulfonium chloride. We are indebted to Elesa Addis (Karnofsky), Mildred Bevelander, Betty Lou Ellis, Vera Hoie, Vera James, Penelope Smith and Lee Summers in the conduct of the experiments.