RT Journal Article
SR Electronic
T1 TISSUE DISTRIBUTION OF A TOXICANT FOLLOWING ORAL INGESTION OF THE GAMMA ISOMER OF BENZENE HEXACHLORIDE BY RATS
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 277
OP 281
VO 93
IS 3
A1 Edwin P. Laug
YR 1948
UL http://jpet.aspetjournals.org/content/93/3/277.abstract
AB 1. Using the house fly as a sensitive test insect, a bio-assay method has been developed for the gamma isomer of benzene hexachloride. 2. Examination of the tissues of rats which had consumed gamma isomer in their diet has shown the presence of a substance having toxicologically identical characteristics to that of the gamma isomer. 3. Largest quantities of toxicant were found in fat and kidney tissues with measurable amounts in blood, liver, spleen, muscle, brain and adrenal. 4. Some excretion of toxicant occurs via the urine but little or none via the feces.