PT - JOURNAL ARTICLE AU - Edwin P. Laug TI - TISSUE DISTRIBUTION OF A TOXICANT FOLLOWING ORAL INGESTION OF THE GAMMA ISOMER OF BENZENE HEXACHLORIDE BY RATS DP - 1948 Jul 01 TA - Journal of Pharmacology and Experimental Therapeutics PG - 277--281 VI - 93 IP - 3 4099 - http://jpet.aspetjournals.org/content/93/3/277.short 4100 - http://jpet.aspetjournals.org/content/93/3/277.full SO - J Pharmacol Exp Ther1948 Jul 01; 93 AB - 1. Using the house fly as a sensitive test insect, a bio-assay method has been developed for the gamma isomer of benzene hexachloride. 2. Examination of the tissues of rats which had consumed gamma isomer in their diet has shown the presence of a substance having toxicologically identical characteristics to that of the gamma isomer. 3. Largest quantities of toxicant were found in fat and kidney tissues with measurable amounts in blood, liver, spleen, muscle, brain and adrenal. 4. Some excretion of toxicant occurs via the urine but little or none via the feces.