RT Journal Article SR Electronic T1 PHARMACOLOGICAL PROPERTIES OF A NEW ANTIHISTAMINIC, 2-METHYL-9-PHENYL-2,3,4,9-TETRAHYDRO-1-PYRIDINDENE (THEPHORIN) AND DERIVATIVES JF Journal of Pharmacology and Experimental Therapeutics JO J Pharmacol Exp Ther FD American Society for Pharmacology and Experimental Therapeutics SP 249 OP 259 VO 92 IS 3 A1 G. LEHMANN YR 1948 UL http://jpet.aspetjournals.org/content/92/3/249.abstract AB Thephorin, 2-methyl-9-phenyl-2,3,4,9-tetrahydro-1-pyridindene, one of three closely related pyridindene derivatives studied, proved to be a potent antihistaminic on isolated guinea pig's ileum, in the spray test, against intracardial histamine and against anaphylactic shock. In addition, Thephorin antagonizes spasmogenic effects of acetyl-choline, of Ba-ions and of epinephrine. 1948 by The American Society for Pharmacology and Experimental Therapeutics