PT  - JOURNAL ARTICLE
AU  - GEORGE H. ACHESON
AU  - SERGIO ARANHA PEREIRA
TI  - THE BLOCKING EFFECT OF TETRAETHYLAMMONIUM ION ON THE SUPERIOR CERVICAL GANGLION OF THE CAT
DP  - 1946 Jul 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 273--280
VI  - 87
IP  - 3
4099  - http://jpet.aspetjournals.org/content/87/3/273.short
4100  - http://jpet.aspetjournals.org/content/87/3/273.full
SO  - J Pharmacol Exp Ther1946 Jul 01; 87
AB  - In cats under dial anesthesia the effects of tetraethylarnmonium bromide were studied on the nictitating membrane and its innervation. This substance does not materially affect the membrane itself or its postganglionic nerves. It produces a block of transmission of nerve impulses across the superior cervical ganglion. The ganglionic stimulating action of acetyicholine is also blocked, but that of potassium ion is not. Unlike curare, many other quaternary ammonium compounds, and nicotine, tetraethylammonium ion has no actions except this specific ganglionic blocking action over a wide range of doses. 1946 by The American Society for Pharmacology and Experimental Therapeutics