TY - JOUR T1 - THE EFFECT OF AMPHETAMINE SULFATE ON PERFORMANCE OF NORMAL AND FATIGUED SUBJECTS JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 106 LP - 108 VL - 89 IS - 2 AU - HENRY W. NEWMAN Y1 - 1947/02/01 UR - http://jpet.aspetjournals.org/content/89/2/106.abstract N2 - Amphetamine sulfate in a dose of 10 mgm. by mouth is incapable of significantly improving performance of a monotonous skilled task for a relatively short time unless this performance has been reduced by previously existing fatigue. In fatigued subjects significant restoration of performance, although not to pre-fatigue levels, usually results from this medication. Thus amphetamine sulfate may be a useful drug when necessity requires the performance of such tasks by fatigued individuals. 1947 by The American Society for Pharmacology and Experimental Therapeutics ER -