RT Journal Article
SR Electronic
T1 METABOLIC STUDIES ON β-CYCLOHEXYLETHYLAMINES
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 389
OP 391
VO 87
IS 4
A1 FRED H. SNYDER
A1 FRED W. OBERST
YR 1946
UL http://jpet.aspetjournals.org/content/87/4/389.abstract
AB 1. α-Methyl substitution of β-cyclohexylethylamine prevents oxidation of the compound in the presence of amine oxidase preparations, and inhibits to a significant extent its destruction following subcutaneous administration to white rats. 2. β-Cyclohexylethylamine and its β-methyl- and N-methyl-β-methyl-derivates are oxidized by amine oxidase, and are almost completely destroyed by the intact animal.