PT  - JOURNAL ARTICLE
AU  - K. GEORGE FALK
AU  - KANEMATSU SUGIURA
TI  - SOME OBSERVATIONS ON THE ELIMINATION OF HEXAMETHYLENETETRAMINE (UROTROPIN)
DP  - 1916 Jan 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 39--51
VI  - 8
IP  - 1
4099  - http://jpet.aspetjournals.org/content/8/1/39.short
4100  - http://jpet.aspetjournals.org/content/8/1/39.full
SO  - J Pharmacol Exp Ther1916 Jan 01; 8
AB  - 1. A method for the estimation of hexamethylenetetramine is described. 2. The total and percentage amounts of hexamethylenetetramine recovered in the urine of normal (average) individuals after administration by mouth were determined and some of the factors involved in the excretion discussed. 3. In general terms, the amount normally excreted is greater the lower the specific gravity of the urine. 4. The concentration of formaldehyde in urine had no apparent connection with the amount of hexamethylenetetramine excreted. 5. In a number of pathological cases involving impairment of kidney function, abnormally small amounts of hexamethylene-tetramine were excreted.