RT Journal Article
SR Electronic
T1 STUDIES ON CYCLOPROPANE IX
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 198
OP 201
VO 85
IS 2
A1 BENJAMIN H. ROBBINS
YR 1945
UL http://jpet.aspetjournals.org/content/85/2/198.abstract
AB 1. An investigation of the blood pressure and electrocardiographic changes has been made in dogs anesthetized with cyclopropane after medication with Demerol. 2. In most dogs there is a reduction in heart rate and temporary fall in blood pressure after the intramuscular injection of 10 mg./kg. of Demerol. 3. The cardiac irregularities routinely observed during cyclopropane anesthesia after morphine premedication in dogs are not observed after Demerol premedication. 4. Demerol reduces the amount of cyclopropane necessary for the lighter planes of anesthesia.