@article {GOVIER143, author = {WM. M. GOVIER and VERA BERGMANN and KARL H. BEYER}, title = {STUDIES ON THE MECHANISM OF ACTION OF SYMPATHOMIMETIC AMINES}, volume = {85}, number = {2}, pages = {143--149}, year = {1945}, publisher = {American Society for Pharmacology and Experimental Therapeutics}, abstract = {1. Succinoxidase of homogenized rat muscle and liver is inhibited by added α-tocopherol phosphate. This effect may be due to diffusion away from the succinoxidase of α-tocopherol originally present in the tissue, upon rupture of the cells during homogenization. 2. Sympathomimetic amines are capable of producing an increase in oxygen uptake by relieving the tocopherol effect. 3. The increase in metabolic activity following the addition of amines to a tocopherol-inhibited succinoxidase system can be used as a source of energy for the synthesis of cocarboxylase from added thiamin and pyrophosphate.}, issn = {0022-3565}, URL = {https://jpet.aspetjournals.org/content/85/2/143}, eprint = {https://jpet.aspetjournals.org/content/85/2/143.full.pdf}, journal = {Journal of Pharmacology and Experimental Therapeutics} }