RT Journal Article SR Electronic T1 A SHORT-TERM CHRONIC TOXICITY TEST EMPLOYING MICE JF Journal of Pharmacology and Experimental Therapeutics JO J Pharmacol Exp Ther FD American Society for Pharmacology and Experimental Therapeutics SP 111 OP 118 VO 85 IS 2 A1 A. C. BRATTON, JR. YR 1945 UL http://jpet.aspetjournals.org/content/85/2/111.abstract AB A method is described for determining the chronic toxicity of drugs when administered to mice for seven days. The use of the drug-diet method of administration, and of death as an end-point, results in a simple procedure for rapid evaluation of large numbers of compounds. The precision of the method is illustrated by data on quinine, quinacrine, and pamaquine.