PT  - JOURNAL ARTICLE
AU  - KURT A. OSTER
AU  - MICHAEL G. MULINOS
TI  - TISSUE ALDEHYDES AND THEIR REACTION WITH AMINES
DP  - 1944 Feb 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 132--138
VI  - 80
IP  - 2
4099  - http://jpet.aspetjournals.org/content/80/2/132.short
4100  - http://jpet.aspetjournals.org/content/80/2/132.full
SO  - J Pharmacol Exp Ther1944 Feb 01; 80
AB  - 1. The staining reaction for aldehydes with fuchsin sulfurous acid is described for liver and kidney tissues of 5 species of animals. 2. The formation of condensation products (Schiff's base) between tissue aldehydes and various amines and the influence of hydrogen ion concentration is described. 3. The significance of the formation of Schiff's base as a detoxification mechanism and the interference of p-amino benzoic acid with the antiseptic powers of the sulfonamides is discussed.