TY - JOUR T1 - A COMPARISON OF THE MECHANISM OF ACTION OF ARSENICALS AND SULFONAMIDES JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 32 LP - 36 VL - 79 IS - 1 AU - LAWRENCE PETERS Y1 - 1943/09/01 UR - http://jpet.aspetjournals.org/content/79/1/32.abstract N2 - The mode of action of sodium p-aminophenylarsonate (atoxyl) on E. coli appears to be similar to that of sulfonamides, since the same mechanisms of antagonism appear to be involved. The bacteriostatic and trypanocidal activities of m-amino-p-hydroxyphenylarsenoxide, `Mapharsen,' apparently are exerted through a different mechanism than that which is involved in the bacteriostatic action of sulfonamides. ER -