PT - JOURNAL ARTICLE AU - BUFORD H. BURCH AU - B. A. WESTFALL TI - INCREASED BLOOD SPECIFIC GRAVITY IN ANESTHETIZED DOGS FOLLOWING PILOCARPINE INJECTIONS DP - 1943 Sep 01 TA - Journal of Pharmacology and Experimental Therapeutics PG - 16--22 VI - 79 IP - 1 4099 - http://jpet.aspetjournals.org/content/79/1/16.short 4100 - http://jpet.aspetjournals.org/content/79/1/16.full SO - J Pharmacol Exp Ther1943 Sep 01; 79 AB - 1. The specific gravity of blood of dogs lying quietly under sodium pentobarbital anesthesia (32.5 mgm./kgm.) rises gradually. 2. Pilocarpine nitrate (0.2 mgm./kgm.) when administered to dogs in deep pentobarbital anesthesia produces a rapid increase in the specific gravity of the blood, the maximal rise being five minutes after the injection of the drug. 3. The spleen, the kidneys and the intestines collectively contribute in the production of this rise in blood specific gravity following injection of pilocarpine into anesthetized dogs. 4. No evidence that the posterior pituitary gland is involved in this rise in blood specific gravity following injections of pilocarpine was obtained during these experiments.