RT Journal Article
SR Electronic
T1 THE COMPARATIVE ACTIVITY OF QUININE, QUINIDINE, CIN-CHONINE, CINCHONIDINE AND QUINOIDINE AGAINS PLASMODIUM LOPHURAE INFECTIONS OF PEKIN DUCKLINGS
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 159
OP 163
VO 78
IS 2
A1 A. O. SEELER
A1 E. DUSENBERY
A1 C. MALANGA
YR 1943
UL http://jpet.aspetjournals.org/content/78/2/159.abstract
AB 1. Quinine, quinidine, cinchonine and cinchonidine show about the same activity against the schizonts of P. lophurae in Pekin ducklings. 2. Quinoidine is considerably less active than the four crystalline cinchona alkaloids. 3. Two samples of totaquine varying widely in their quinine content were as active as quinine in duck malaria. 4. There is little difference in the acute oral toxicity for mice among the four crystalline alkaloids. Quinoidine is more toxic than the crystalline alkaloids.