TY - JOUR T1 - PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES ON <em>l-N</em>-ETHYLEPHEDRINE HYDROCHLORIDE JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 289 LP - 298 VL - 75 IS - 3 AU - T. J. BECKER AU - M. R. WARREN AU - D. G. MARSH AU - C. R. THOMPSON AU - R. S. SHELTON Y1 - 1942/07/01 UR - http://jpet.aspetjournals.org/content/75/3/289.abstract N2 - The toxicological and pharmacological actions of l-N-ethylephedrine have been described and compared with those of l-ephedrine. The toxicity of this compound is of the same order as that of l-ephedrine. The effect on the cardiovascular system is less than that elicited by similar amounts of l-ephedrine whereas the effect on the bronchioles is approximately the same. l-N-Ethylephedrine appears to have a greater effect on the intestinal and uterine muscle than l-ephedrine. This compound produces a minimum of central stimulation. An attempt has been made to correlate the pharmacological actions of l-N-ethylephedrine with its chemical structure. ER -