RT Journal Article
SR Electronic
T1 THE THERAPEUTIC EFFECT OF SULFACETIMIDE IN EXPERIMENTAL INFECTIONS DUE TO ESCHERICHIA COLI
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 173
OP 175
VO 73
IS 2
A1 RICHARD DONOVICK
A1 EDWARD HENDERSON
YR 1941
UL http://jpet.aspetjournals.org/content/73/2/173.abstract
AB On the basis of equal oral dosage sulfacetimide produced higher survival rates than sulfanilamide in mice experimentally infected with Escherichia coli. However, since the blood concentration-time curves obtained with the dosage schedule employed may be dissimilar for the two drugs, it cannot be presumed from these experiments that sulfacetimide is more active therapeutically than sulfanilamide in this infection.