RT Journal Article
SR Electronic
T1 THE RESPONSE OF SULFAPYRIDINE-RESISTANT PNEUMOCOCCI TO HYDROXYETHYLAPOCUPREINE
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 311
OP 316
VO 72
IS 3
A1 L. H. SCHMIDT
A1 CLARA L. SESLER
YR 1941
UL http://jpet.aspetjournals.org/content/72/3/311.abstract
AB A comparison was made of the activity of hydroxyethylapocupreine and sulfapyridine against infections in mice with parent and sulfapyridine-fast pneumococci. Infections with the parent organisms were susceptible to treatment with sulfapyridine, whereas infections with the "fast" organisms were not. On the other hand, hydroxyethylapocupreine was equally effective against infections with parent and sulfapyridine-resistant strains. However, hydroxyethylapocupreine was less effective than sulfapyridine against infections with most of the parent organisms.