RT Journal Article
SR Electronic
T1 FURTHER STUDIES ON THE FATE OF SELENIUM IN THE ORGANISM
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 245
OP 251
VO 72
IS 3
A1 BENTON B. WESTFALL
A1 M. I. SMITH
YR 1941
UL http://jpet.aspetjournals.org/content/72/3/245.abstract
AB 1. A method for the fractionation of urinary selenium which distinguishes sodium selenate and selenite from organic selenium has been presented. 2. Most of the urinary selenium excreted by rabbits fed on seleniferous wheat appears with the ethereal and neutral sulfur presumably as organic selenium, with only about 15 per cent as inorganic. 3. Various agents reputed to influence the sulfur partition of the urine produced no marked change in the urinary selenium output. 4. No significant increase in the output of urinary selenium or any decrease in the tissue selenium could be obtained by the oral administration of brombenzene. 5. No pronounced amounts of selenium could be found with p-brom-phenyl mercapturic acid isolated from the urine of brombenzene-treated selenized rabbits.