RT Journal Article
SR Electronic
T1 THE ANESTHETIC ACTIVITY OF OPTICAL ANTIPODES II. THE ARABINOCHLORALOSES
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 229
OP 235
VO 69
IS 3
A1 THOMAS C. BUTLER
YR 1940
UL http://jpet.aspetjournals.org/content/69/3/229.abstract
AB By reaction of chloral with d- and with l-arabinose, four isomeric arabinochloraloses (two pairs of antipodes) have been obtained. The four compounds have been tested as anesthetics in mice. α-l-Arabinochloralose is much more active than its antipode. β-d-Arabinochloralose is somewhat more active than its antipode. The significance of the unequal activity of the antipodes in relation to the theories of narcosis is discussed.