RT Journal Article
SR Electronic
T1 RATE OF DISAPPEARANCE OF PITUITARY GONADOTROPHIN FROM THE BLOOD OF RABBITS
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 433
OP 439
VO 70
IS 4
A1 J. M. ROBSON
A1 A. I. S. MACPHERSON
YR 1940
UL http://jpet.aspetjournals.org/content/70/4/433.abstract
AB Gonadotrophin from horse pituitaries was injected intravenously into rabbits, and the disappearance of the hormone from the blood and excretion in the urine determined. Less than half of the injected amount could be detected in the serum within 6 hours, and only small amounts were present after 24 hours. Some 10 to 20 per cent of the injected hormone was recovered from the urine. A similar experiment performed on a child with a meningocoele showed that the hormone rapidly disappeared from the serum and that little of it was excreted in the urine.