PT  - JOURNAL ARTICLE
AU  - DONALD SLAUGHTER
AU  - DONALD W. MUNSELL
TI  - SOME NEW ASPECTS OF MORPHINE ACTION EFFECTS ON PAIN
DP  - 1940 Jan 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 104--112
VI  - 68
IP  - 1
4099  - http://jpet.aspetjournals.org/content/68/1/104.short
4100  - http://jpet.aspetjournals.org/content/68/1/104.full
SO  - J Pharmacol Exp Ther1940 Jan 01; 68
AB  - 1. Morphine effect is potentiated by Prostigmin when pressure-pain responses in the cat are determined. 2. Atropine antagonizes the effect of morphine or of a morphine-Prostigmin combination. 3. Evidence is presented to show that morphine fits many of the postulates necessary for a cholinergic drug. 4. Statistical analyses as to probability ("P") correlate well with result averages. 5. The mechanism of morphine action as an acetylcholine-like drug is discussed. 6. Practical application of these results is suggested.