@article {BUTLER205, author = {THOMAS C. BUTLER and MILTON T. BUSH}, title = {THE METABOLIC FATE OF N-METHYLBARBITURIC ACIDS}, volume = {65}, number = {2}, pages = {205--213}, year = {1939}, publisher = {American Society for Pharmacology and Experimental Therapeutics}, abstract = {After intravenous injections in dogs of anesthetic doses of N-methylbarbital, N-methylphenobarbital, and N,N{\textquoteright}-dimethylbarbital there have been recovered from the urine considerable amounts of the corresponding 5,5-disubstituted barbituric acids. The significance of this demethylation with regard to the duration of action of N-methylbarbituric acids has been discussed.}, issn = {0022-3565}, URL = {https://jpet.aspetjournals.org/content/65/2/205}, eprint = {https://jpet.aspetjournals.org/content/65/2/205.full.pdf}, journal = {Journal of Pharmacology and Experimental Therapeutics} }