TY - JOUR T1 - STUDIES OF CYCLOPROPANE V. THE EFFECT OF MORPHINE, BARBITAL, AND AMYTAL UPON THE CONCENTRATION OF CYCLOPROPANE IN THE BLOOD REQUIRED FOR ANESTHESIA AND RESPIRATORY ARREST JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 136 LP - 142 VL - 65 IS - 2 AU - BENJAMIN H. ROBBINS AU - J. H. BAXTER, JR. AU - O. GARTH FITZHUGH Y1 - 1939/02/01 UR - http://jpet.aspetjournals.org/content/65/2/136.abstract N2 - The effect of premedication with morphine, barbital, or amytal upon the concentration of cyclopropane in the blood necessary for the different levels of anesthesia and respiratory arrest has been determined on 28 dogs. With the smaller doses of the drugs used there was a marked reduction in the amount of cyclopropane necessary for surgical anesthesia without an appreciable reduction in the concentration necessary to produce respiratory arrest. With the larger doses of the drugs used, partial summation was present in all stages and at respiratory arrest. ER -