PT  - JOURNAL ARTICLE
AU  - J. RAVENTÓS
TI  - THE INFLUENCE OF ROOM TEMPERATURE ON THE ACTION OF BARBITURATES
DP  - 1938 Dec 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 355--363
VI  - 64
IP  - 4
4099  - http://jpet.aspetjournals.org/content/64/4/355.short
4100  - http://jpet.aspetjournals.org/content/64/4/355.full
SO  - J Pharmacol Exp Ther1938 Dec 01; 64
AB  - 1. The duration of action of sodium evipan on mice (3 x h.d.50 given intraperitoneally) is dependent on the room temperature (Dur. 20°C./Dur.30°C. = 2.4). 2. The l.d.50 of phenobarbitone at 20°C. is about ⅔ that at 30°C. 3. Comparisons between the biological properties of barbiturate compounds should be carried out at a uniform room temperature and 30°C. seems preferable to 20°C.