TY - JOUR T1 - THE EFFECT OF COFFEE AND DECAFFEINATED COFFEE ON OXYGEN CONSUMPTION, PULSE RATE AND BLOOD PRESSURE JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 294 LP - 304 VL - 58 IS - 3 AU - KATHRYN HORST AU - ROBERT J. WILLSON AU - RALPH G. SMITH Y1 - 1936/11/01 UR - http://jpet.aspetjournals.org/content/58/3/294.abstract N2 - In 26 experiments on 14 human subjects under basal conditions in which oxygen consumption was measured before decaffeinated coffee was taken and one-half hour and one and one-half hours after, little, if any, change was found following the beverage in the majority of cases. In an equal number of experiments on the same subjects in which coffee (equivalent to 4 mgm. per kilogram of caffeine) was taken, a definite increase in oxygen consumption was recorded for both periods following the drinking of the beverage (one-half hour period, +8 per cent; one and one-half hour period, +9 per cent). In the same experiments, decaffeinated coffee produced negligible and inconstant changes on pulse rate and blood pressure whereas coffee, in the majority of instances produced a slight decrease in pulse rate and a slight rise in blood pressure. ER -