PT  - JOURNAL ARTICLE
AU  - KATHRYN HORST
AU  - ROBERT J. WILLSON
AU  - RALPH G. SMITH
TI  - THE EFFECT OF COFFEE AND DECAFFEINATED COFFEE ON OXYGEN CONSUMPTION, PULSE RATE AND BLOOD PRESSURE
DP  - 1936 Nov 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 294--304
VI  - 58
IP  - 3
4099  - http://jpet.aspetjournals.org/content/58/3/294.short
4100  - http://jpet.aspetjournals.org/content/58/3/294.full
SO  - J Pharmacol Exp Ther1936 Nov 01; 58
AB  - In 26 experiments on 14 human subjects under basal conditions in which oxygen consumption was measured before decaffeinated coffee was taken and one-half hour and one and one-half hours after, little, if any, change was found following the beverage in the majority of cases. In an equal number of experiments on the same subjects in which coffee (equivalent to 4 mgm. per kilogram of caffeine) was taken, a definite increase in oxygen consumption was recorded for both periods following the drinking of the beverage (one-half hour period, +8 per cent; one and one-half hour period, +9 per cent). In the same experiments, decaffeinated coffee produced negligible and inconstant changes on pulse rate and blood pressure whereas coffee, in the majority of instances produced a slight decrease in pulse rate and a slight rise in blood pressure.