RT Journal Article
SR Electronic
T1 THE LOCAL ANAESTHETIC ACTIVITY OF QUINOLINE COMPOUNDS
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 62
OP 67
VO 58
IS 1
A1 H. K. SINHA
YR 1936
UL http://jpet.aspetjournals.org/content/58/1/62.abstract
AB My results, combined with those of Bovet, show that a large number of quinoline compounds with a basic side chain of adequate length in position 8 produce a strong local anaesthetic action, both when applied to mucous membranes and when injected intradermally. My results also show that side chains with two amine groups are more effective than side chains containing a single amine group.