PT - JOURNAL ARTICLE AU - V. E. HALL AU - P. E. CHAMBERLIN TI - THE SYNERGIC CALORIGENIC ACTIONS OF EPINEPHRINE AND DINITROPHENOL DP - 1937 Apr 01 TA - Journal of Pharmacology and Experimental Therapeutics PG - 451--457 VI - 59 IP - 4 4099 - http://jpet.aspetjournals.org/content/59/4/451.short 4100 - http://jpet.aspetjournals.org/content/59/4/451.full SO - J Pharmacol Exp Ther1937 Apr 01; 59 AB - In anesthetized cats the increase in oxygen consumption rate caused by dinitrophenol is markedly greater if epinephrine be infused intravenously at a physiological rate during, or just before, the period of dinitrophenol action. The enhancement so produced is significantly greater than the increase in oxygen consumption yielded by epinephrine alone. This synergic calorigenic action is a major factor in the enhancement of dinitrophenol metabolic stimulation observed in hypothermic animals.