PT  - JOURNAL ARTICLE
AU  - JAMES W. SACHS
AU  - JOSEPH McK. IVIE
TI  - THE EFFECT OF ACID ON THE GUINEA PIG ILEUM CONTRACTED BY ACETYLCHOLINE AND HISTAMINE
DP  - 1936 Jul 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 253--257
VI  - 57
IP  - 3
4099  - http://jpet.aspetjournals.org/content/57/3/253.short
4100  - http://jpet.aspetjournals.org/content/57/3/253.full
SO  - J Pharmacol Exp Ther1936 Jul 01; 57
AB  - 1. Approximately twice the amount of acetic acid is needed to relax an intestinal strip when contracted by acetylcholine than when contracted by histamine. 2. The amount of acid necessary to cause relaxation is dependent within limits on the amount of histamine but independent of the amount of acetylcholine used. 3. Lactic acid has the same effect as acetic acid. 4. Increasing the calcium concentration has no effect on the acid relaxation.