TY - JOUR T1 - THE ACTION OF THE ENZYMES OF THE VENOM OF CROTALUS ADAMANTEUS ON THE PROTEINS OF BLOOD AND MILK JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 386 LP - 392 VL - 50 IS - 4 AU - EDWIN E. DUNN Y1 - 1934/04/01 UR - http://jpet.aspetjournals.org/content/50/4/386.abstract N2 - 1. The venom of Crotalus adamanteus contains one or more proteolytic enzymes which digest plasma and serum proteins, and, with less rapidity, crystallized serum albumin and fibrin. The proteinase studied here is probably different from that which acts with such speed on fibrinogen. 2. The venom has a weak but definite rennin action. Although the casein of the coagulated milk appears to be digested only to a slight extent, dissolved purified casein is rapidly and completely digested. 3. Crotalus venom transforms hemoglobin into methemoglobin, both in hemolyzed erythrocytes and in hemoglobin solution. ER -