RT Journal Article
SR Electronic
T1 STUDIES ON THE DENERVATED KIDNEY I. THE ACTION OF CINCHOPHEN ON THE URIC ACID AND ALLANTOIN EXCRETION IN DOGS, AND ITS EFFECT ON THE NITROGEN AND SULPHUR EXCRETION
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 123
OP 130
VO 50
IS 1
A1 G. P. GRABFIELD
A1 MILDRED G. GRAY
YR 1934
UL http://jpet.aspetjournals.org/content/50/1/123.abstract
AB 1. The effects of cinchophen on the uric acid and allantoin secretion in three dogs on a constant diet was determined before and after denervation of both kidneys. 2. The effect of cinchophen on the allantoin excretion is, if anything, slightly enhanced by section of the renal nerves. 3. There is a reversal of the effect of cinchophen on the uric acid excretion after denervation of the kidneys. This reversal of effect returns to normal after a varying period which may be associated with regeneration of the renal nerves. 4. Experiments are cited to show that the increase in the urinary nitrogen and sulphur excretion produced by the exhibition of cinchophen is not altered by denervation of the kidneys.