RT Journal Article SR Electronic T1 THE EFFECT OF CALCIUM ON THE RESPONSE OF ISOLATED BRONCHI TO HISTAMINE JF Journal of Pharmacology and Experimental Therapeutics JO J Pharmacol Exp Ther FD American Society for Pharmacology and Experimental Therapeutics SP 419 OP 426 VO 45 IS 4 A1 MARJORIE GILLESPIE A1 J. W. THORNTON YR 1932 UL http://jpet.aspetjournals.org/content/45/4/419.abstract AB 1. It has been shown that the isolated bronchial muscle of guinea pigs is sensitive to changes as low as 1 mgm. per cent in ionic concentration of calcium as measured by the response to histamine. 2. A seasonal variation in the response to histamine in guinea pigs has been noted. 3. The significance of these factors is discussed.