RT Journal Article
SR Electronic
T1 THE RELATION OF VASCULAR CONDITIONS TO PITUITRIN DIURESIS
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 435
OP 441
VO 4
IS 5
A1 R. G. HOSKINS
A1 JOHN W. MEANS
YR 1913
UL http://jpet.aspetjournals.org/content/4/5/435.abstract
AB 1. Pituitrin in suitable dosage causes diuresis in the anesthetised dog. 2. There is no constant relationship between pituitrin diuresis and either systolic pressure or pulse pressure or the ratio between them, although 3. Pituitrin diuresis usually is accompanied by decreased pulse pressure. Previous researches (Schaefer and Herring) have shown that there is no constant relationship between changes of kidney volume and pituitary diuresis. 4. Pituitrin diuresis, therefore, is due primarily to direct stimulation of the renal cells—usually aided, probably, by a concomitant vasodilation in the kidneys.