PT  - JOURNAL ARTICLE
AU  - HADDOW M. KEITH
TI  - FURTHER STUDIES OF THE CONTROL OF EXPERIMENTALLY PRODUCED CONVULSIONS
DP  - 1932 Apr 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 449--455
VI  - 44
IP  - 4
4099  - http://jpet.aspetjournals.org/content/44/4/449.short
4100  - http://jpet.aspetjournals.org/content/44/4/449.full
SO  - J Pharmacol Exp Ther1932 Apr 01; 44
AB  - In rabbits the anticonvulsive effect of diacetone alcohol given by mouth is definite. A considerably larger amount of it is required than is required of phenobarbital to produce a similar effect. The latter, however, is much more toxic in larger doses, and causes considerably more irritability to sensory stimuli. The anticonvulsive properties of diacetone alcohol depend on the acetone portion of the molecule. β-hydroxybutyric acid, in itself, is not anticonvulsive.