PT - JOURNAL ARTICLE AU - F. E. D'AMOUR AU - R. G. GUSTAVSON TI - A CRITICAL STUDY OF THE ASSAY OF FEMALE SEX HORMONE PREPARATIONS DP - 1930 Dec 01 TA - Journal of Pharmacology and Experimental Therapeutics PG - 473--484 VI - 40 IP - 4 4099 - http://jpet.aspetjournals.org/content/40/4/473.short 4100 - http://jpet.aspetjournals.org/content/40/4/473.full SO - J Pharmacol Exp Ther1930 Dec 01; 40 AB - 1. The necessity of an international agreement on a method for measuring oestrin has been discussed. 2. The work of Coward and Burn in general has been confirmed. 3. Various factors which influence the accuracy of the measuremrnt have been studied. 4. A reproducible rat unit may be determined from the standard curve obtained by the method of Coward and Burn provided it is recognized that errors will ensue if a small number of animals is used or if only a small percentage of a large number of animals responds positively.