RT Journal Article SR Electronic T1 Experimental Therapeutics in the Renaissance JF Journal of Pharmacology and Experimental Therapeutics JO J Pharmacol Exp Ther FD American Society for Pharmacology and Experimental Therapeutics SP 489 OP 492 DO 10.1124/jpet.102.042291 VO 304 IS 2 A1 Stata Norton YR 2003 UL http://jpet.aspetjournals.org/content/304/2/489.abstract AB Detailed accounts of therapeutics at the time of the European Renaissance written by the participants have not survived in large numbers. One manuscript, dated 1562, was written by friars in a religious order in Italy dedicated to the care of the sick. Their remedies, methods of preparation, and uses were detailed by the friars and offer a glimpse into the beginnings of experimentation with drugs and rejection of tradition and authority in determining the effectiveness of a remedy. These developing concepts were combined in the manuscript with traditional treatments dating back through the Middle Ages to the medical methods of Greece and Rome. The American Society for Pharmacology and Experimental Therapeutics