TY - JOUR T1 - THE CONTROL OF THE MOTILITY OF THE HUMAN STOMACH BY DRUGS AND OTHER MEANS JF - Journal of Pharmacology and Experimental Therapeutics JO - J Pharmacol Exp Ther SP - 33 LP - 51 VL - 24 IS - 1 AU - W. H. DICKSON AU - M. J. WILSON Y1 - 1924/08/01 UR - http://jpet.aspetjournals.org/content/24/1/33.abstract N2 - 1. Gastric peristalsis can be inhibited wholly or in part by violent exercise, by raising the CO2 content of inspired air, and by very large doses of NaHCO3. 2. It is markedly increased by forced breathing and to a lesser extent by very large doses of NH4Cl. 3. Evidence is presented by analysis of the alveolar air to show that changes in the tension of CO2 in the arterial blood may be responsible for the inhibition or augmentation of the contractions in the above cases. 4. Gastric inhibition always follows excessive smoking, and sometimes the subcutaneous injection of epinephrin. Augmentation always occurs after the administration of coffee, whiskey and strychnine in ordinary amounts, and after very large doses of MgO. 5. Insulin very markedly increases gastric peristalsis. 6. The pharmacological action of therapeutic doses of the so-called alkalis remains obscure. ER -