RT Journal Article
SR Electronic
T1 Marihuana smoking suppresses luteinizing hormone in women.
JF Journal of Pharmacology and Experimental Therapeutics
JO J Pharmacol Exp Ther
FD American Society for Pharmacology and Experimental Therapeutics
SP 862
OP 866
VO 237
IS 3
A1 J H Mendelson
A1 N K Mello
A1 J Ellingboe
A1 A S Skupny
A1 B W Lex
A1 M Griffin
YR 1986
UL http://jpet.aspetjournals.org/content/237/3/862.abstract
AB Smoking a single 1-g marihuana cigarette containing 1.8% delta 9-tetrahydrocannabinol induced a 30% suppression of plasma luteinizing hormone levels (P less than .02) in women during the luteal phase of the menstrual cycle. After marihuana placebo cigarette smoking, no luteinizing hormone suppression was observed in the same women under double-blind conditions. Marihuana may have adverse effects upon reproductive function during the luteal phase of the menstrual cycle as a consequence of gonadotropin inhibition.