PT  - JOURNAL ARTICLE
AU  - L Levy
AU  - D McClure
TI  - The pharmacology of flazalone: a new class of anti-inflammatory agent.
DP  - 1976 Aug 01
TA  - Journal of Pharmacology and Experimental Therapeutics
PG  - 473--480
VI  - 198
IP  - 2
4099  - http://jpet.aspetjournals.org/content/198/2/473.short
4100  - http://jpet.aspetjournals.org/content/198/2/473.full
SO  - J Pharmacol Exp Ther1976 Aug 01; 198
AB  - The anti-inflammatory activity of flazalone, a unique chemical drug, is described. In acute irritant anti-inflammatory tests, flazalone exhibited a wide spectrum of activity. The compound was active in affecting the course of paw swelling in adjuvant arthritis when given daily either at the outset of the polyarthritis or after induction. The most unusual aspect of this compound is its ability to inhibit graft rejection in goldfish and rabbits. The pattern of anti-inflammatory activity does not allow one to classify this drug in the usual groups.